Searchable abstracts of presentations at key conferences in endocrinology

ea0028p382 | Thyroid | SFEBES2012

Removal of heterophilic antibody interference in thyroid function tests with heterophilic blocking tubes

Armston Annie , Hyde Sarah , Day Linda

Heterophilic antibodies are human immunoglobulins with antigenic determinants directed against non-human species. These antibodies can interfere with the measurement of analytes in routine clinical laboratories, in particular in 2-site immunoassays. Skybio heterophilic blocking tubes-50 (HBT-50) are one way of overcoming this interference but, it has been reported (Sturgeon and Viljoen, Annals Clin Biochem, 2011, 48, 418), some samples may require two treatments to completely ...